IMPERIAL CRS

5 5 The ROAR Study WEEKLY DIARY LOG Complete the Headache Log every day. If you experience one or more headaches on a given day, record the details in the Headache Details table. If more than 3 days have passed since you made a diary entry, please leave the diary blank for those dates. HEADACHE LOG Week Number Subject Number Date (MM/DD/YYYY) Were any headaches experienced? Number of headaches / / Yes No / / Yes No / / Yes No / / Yes No / / Yes No / / Yes No / / Yes No HEADACHE DETAILS Answer the questions below for each headache that you experience. If you answer yes to, "Did you take any non-study medication to treat this headache?", enter the medication(s) in the medication(s) taken section. Headache number 1 START date and time for this headache: Date / / Time : AM PM END date and time for this headache: Date / / Time : AM PM What was the intensity of pain for this headache? (indicate 0-10 using scale) Did your pain pulsate, pound, or throb? Was your pain mostly on one side or both sides of your head? What was maximum severity of nausea for this headache? What was maximum severity of vomiting for this headache? What was maximum severity of sensitivity to light for this headache? What was maximum severity of sensitivity to sound for this headache? Was this headache worsened by activity or cause you to avoid activity? Did you experience aura with this headache? If yes, did the aura symptom spread gradually over several minutes? If yes, how long did the aura last? Did you take any non-study medications to treat this headache? Yes No Right side Left side Both sides None Mild Moderate Severe None Mild Moderate Severe None Mild Moderate Severe None Mild Moderate Severe Yes No Yes No Yes No mins Yes No Medication(s) taken Date taken Times(s) taken a NSAID Acetaminophen Combination Analgesic Triptan Ergotamine / / b NSAID Acetaminophen Combination Analgesic Triptan Ergotamine / / c NSAID Acetaminophen Combination Analgesic Triptan Ergotamine / / Headache number 2 START date and time for this headache: Date / / Time : AM PM END date and time for this headache: Date / / Time : AM PM What was the intensity of pain for this headache? (indicate 0-10 using scale) Did your pain pulsate, pound, or throb? Was your pain mostly on one side or both sides of your head? What was maximum severity of nausea for this headache? What was maximum severity of vomiting for this headache? What was maximum severity of sensitivity to light for this headache? What was maximum severity of sensitivity to sound for this headache? Was this headache worsened by activity or cause you to avoid activity? Did you experience aura with this headache? If yes, did the aura symptom spread gradually over several minutes? If yes, how long did the aura last? Did you take any non-study medications to treat this headache? Yes No Right side Left side Both sides None Mild Moderate Severe None Mild Moderate Severe None Mild Moderate Severe None Mild Moderate Severe Yes No Yes No Yes No mins Yes No Medication(s) taken Date taken Times(s) taken a NSAID Acetaminophen Combination Analgesic Triptan Ergotamine / / b NSAID Acetaminophen Combination Analgesic Triptan Ergotamine / / c NSAID Acetaminophen Combination Analgesic Triptan Ergotamine / / If you experience more than two headaches this week, use the additional logs on the next page to record your information.

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