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All Rights Reserved 2023. p.4 cardiology p.8 immunology p.14 oncology p.5 dermatology For more information, or to see if you may qualify, call ABC Research at (877) 123-4567 or visit www.novartisclinicaltrials.com Ever wish you were invisible? If you have plaque psoriasis, you know the feel- ing. Red, inflamed, scaly skin can make you want to retreat from the world. But why live in the shadows? You could participate in exciting research under way in your area. Doctors are studying the safety, effectiveness and length of response of an investigational drug for chronic plaque psoriasis. Doctors for this clinical trial seek participants who: • Are 18 to 65 years old • Have had plaque psoriasis for at least 6 months • Are in good general health Participants will receive trial-related medication, monitoring and care at no cost. Join efforts to potentially identify new psoriasis treatments. p.10 inflammatory p.6 endocrinology p.12 neurology p.18 pulmonology p.17 pain p.16 ophthalmology p.20 pediatrics p.22 branding Our Creative Process Imperial creates content with facts, not fluff, so our research must be sound. Following client consultation, every assignment gets underway with thorough review of the protocol and in- depth research of the disease indication and target audience. From the etymology of words in messaging to the cultural connotation of color in designs, efforts in the research realm inspire accuracy and targeted campaigns. Our efforts have yielded many awards for creative excellence including ten international honors for concept, writing and design. Following is a sampling of materials we created for various therapeutic areas. For details about Imperial's comprehensive disease experience, call us at 800.777.2591. Table of Contents 3